Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

Abstract

Background
Patients with heart failure and iron deficiency have diverse causes for hospitalization and death that might be affected by iron repletion.

Objectives:
The purpose of this study was to explore causes of hospitalizations and deaths in a randomized trial (IRONMAN) of heart failure comparing intravenous ferric derisomaltose (FDI) (n = 568) and usual care (n = 569).

Methods:
Patients with heart failure, left ventricular ejection fraction ≤45%, and either transferrin saturation <20% or serum ferritin <100 μg/L were enrolled. Median follow-up was 2.7 years (Q1-Q3: 1.8-3.6 years). A committee adjudicated the main and contributory causes of unplanned hospitalizations and deaths. RRs (rate ratios) for selected recurrent events with 95% CIs are also reported.

Results:
Compared with usual care, patients randomized to FDI had fewer unplanned hospitalizations (RR: 0.83; 95% CI: 0.71-0.97; P = 0.02), with similar reductions in cardiovascular (RR: 0.83; 95% CI: 0.69-1.01) and noncardiovascular (RR: 0.83; 95% CI: 0.67-1.03) hospitalizations, as well as hospitalizations for heart failure (RR: 0.78; 95% CI: 0.60-1.00), respiratory disease (RR: 0.70; 95% CI: 0.53-0.97), or infection (RR: 0.82; 95% CI: 0.66-1.03). Heart failure was the main cause for 26% of hospitalizations and contributed to or complicated a further 12%. Infection caused or contributed to 38% of all hospitalizations, including 27% of heart failure hospitalizations. Patterns of cardiovascular and all-cause mortality were similar for patients assigned to FDI or usual care.

Conclusions:
In IRONMAN, FDI exerted similar reductions in cardiovascular and noncardiovascular hospitalizations, suggesting that correcting iron deficiency might increase resistance or resilience to a broad range of problems that cause hospitalizations in patients with heart failure. (Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency; NCT02642562)

People
Cleland, John
Author

Taylor, Rod and Burrell, Emma and O’Hare, Claire and Thomson, Elizabeth and Placzek, Anna and Bollen, Jessica and Cleland, John G.F. and Cowie, Ansley and Dalal, Hasnain and Deaton, Christi and Doherty, Patrick and Dudman, Katie and Fraser, Heather and Frost, Julia and Greaves, Colin J. and Hartshorne-Evans, Nick and Hillsdon, Melvyn and Ibbotson, Tracy and Jarallah, Mohammad and Jolly, Kate and McConnachie, Alex and McIntosh, Emma and Smith, Valerie and Squire, Iain and Taylor, Louise and van Beurden, Sam and Lang, Chim C. and REACH-HFpEF investigators (2025) Clinical effectiveness and cost-effectiveness of the rehabilitation enablement in chronic heart failure facilitated self-care rehabilitation intervention for people with heart failure with preserved ejection fraction and their caregivers: rationale and protocol for a multicentre randomised controlled trial – REACH-HFpEF trial. BMJ Open, 15 (5): e094254. ISSN 2044-6055

Monzo, Luca and Kobayashi, Masatake and Ferreira, João Pedro and Lamiral, Zohra and Delles, Christian and Clark, Andrew L. and Edelmann, Frank and González, Arantxa and Heymans, Stephane and Pellicori, Pierpaolo and Petutschnigg, Johannes and Verdonschot, Job A. J. and Rossignol, Patrick and Cleland, John and Zannad, Faiez and Girerd, Nicolas (2025) Echocardiographic and biomarker characteristics in diabetes, coronary artery disease or both: insights from HOMAGE trial. Cardiovascular Diabetology, 24: 111. ISSN 1475-2840

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Pellicori, Pierpaolo
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

Caiazzo, Elisabetta and Sharma, Malvika and Rezig, Asma O.M. and Morsy, Moustafa I. and Czesnikiewicz-Guzik, Marta and Ialenti, Armando and Sulicka-Grodzicka, Joanna and Pellicori, Pierpaolo and Crouch, Simone H. and Schutte, Aletta E. and Bruzzese, Dario and Maffia, Pasquale and Guzik, Tomasz J. (2023) Circulating cytokines and risk of developing hypertension: a systematic review and meta-analysis. Pharmacological Research, 200: 107050. ISSN 1043-6618

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Graham, Fraser J.
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Lane, Rebecca
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Petrie, Mark C.
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Ahmed, Fozia
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Squire, Iain B.
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Ludman, Andrew
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Japp, Alan
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

Henriksen, Peter A. and Hall, Peter and MacPherson, Iain R. and Joshi, Shruti S. and Singh, Trisha and Maclean, Morag and Lewis, Steff and Rodriguez, Aryelly and Fletcher, Alexander and Everett, Russell J. and Stavert, Harriet and Broom, Angus and Eddie, Lois and Primrose, Lorraine and McVicars, Heather and McKay, Pam and Borley, Annabel and Rowntree, Clare and Lord, Simon and Collins, Graham and Radford, John and Guppy, Amy and Williams, Michelle C. and Japp, Alan and Payne, John R. and Newby, David E. and Mills, Nick L. and Oikonomidou, Olga and Lang, Ninian N. (2023) Multicenter, prospective, randomized controlled trial of high-sensitivity cardiac troponin I–guided combination angiotensin receptor blockade and beta-blocker therapy to prevent anthracycline cardiotoxicity: The Cardiac CARE trial. Circulation, 148 (21). pp. 1680-1690. ISSN 0009-7322

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Al-Mohammad, Abdallah
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Clark, Andrew L.
Author

Monzo, Luca and Kobayashi, Masatake and Ferreira, João Pedro and Lamiral, Zohra and Delles, Christian and Clark, Andrew L. and Edelmann, Frank and González, Arantxa and Heymans, Stephane and Pellicori, Pierpaolo and Petutschnigg, Johannes and Verdonschot, Job A. J. and Rossignol, Patrick and Cleland, John and Zannad, Faiez and Girerd, Nicolas (2025) Echocardiographic and biomarker characteristics in diabetes, coronary artery disease or both: insights from HOMAGE trial. Cardiovascular Diabetology, 24: 111. ISSN 1475-2840

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Szwejkowski, Ben
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Critoph, Chris
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Chong, Victor
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Schiff, Rebekah
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Nageh, Thuraia
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Glover, Jason
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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McMurray, John J.V.
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Thomson, Elizabeth A.
Author

Taylor, Rod and Burrell, Emma and O’Hare, Claire and Thomson, Elizabeth and Placzek, Anna and Bollen, Jessica and Cleland, John G.F. and Cowie, Ansley and Dalal, Hasnain and Deaton, Christi and Doherty, Patrick and Dudman, Katie and Fraser, Heather and Frost, Julia and Greaves, Colin J. and Hartshorne-Evans, Nick and Hillsdon, Melvyn and Ibbotson, Tracy and Jarallah, Mohammad and Jolly, Kate and McConnachie, Alex and McIntosh, Emma and Smith, Valerie and Squire, Iain and Taylor, Louise and van Beurden, Sam and Lang, Chim C. and REACH-HFpEF investigators (2025) Clinical effectiveness and cost-effectiveness of the rehabilitation enablement in chronic heart failure facilitated self-care rehabilitation intervention for people with heart failure with preserved ejection fraction and their caregivers: rationale and protocol for a multicentre randomised controlled trial – REACH-HFpEF trial. BMJ Open, 15 (5): e094254. ISSN 2044-6055

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Robertson, Michele
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Ford, Ian
Author

Muir, Keith and Ford, Gary A. and Ford, Ian and Wardlaw, Joanna M. and McConnachie, Alex and Greenlaw, Nicola and Mair, Grant and Sprigg, Nikola and Price, Christopher I. and MacLeod, Mary Joan and Dima, Sofia and Venter, Marius and Zhang, Liqun and O’Brien, Eoin and Sanyal, Ranjan and Reid, John and Sztriha, Laszlo K. and Haider, Syed and Whiteley, William N. and Kennedy, James and Perry, Richard and Marigold, Richard and Raghunathan, Senthil and Sims, Don and Bhandari, Mohit and Wiggam, Ivan and Rashed, Khalid and Douglass, Chris (2024) Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial. Lancet Neurology, 23 (11). pp. 1087-1096. ISSN 1474-4422

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Kalra, Philip A.
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Kalra, Paul R.
Author

Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R. (2024) Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure. Journal of the American College of Cardiology, 84 (18). pp. 1704-1717. ISSN 0735-1097

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Title:
Adjudication of hospitalizations and deaths in the IRONMAN Trial of intravenous iron for heart failure
Creators:
Cleland, John and Pellicori, Pierpaolo and Graham, Fraser J. and Lane, Rebecca and Petrie, Mark C. and Ahmed, Fozia and Squire, Iain B. and Ludman, Andrew and Japp, Alan and Al-Mohammad, Abdallah and Clark, Andrew L. and Szwejkowski, Ben and Critoph, Chris and Chong, Victor and Schiff, Rebekah and Nageh, Thuraia and Glover, Jason and McMurray, John J.V. and Thomson, Elizabeth A. and Robertson, Michele and Ford, Ian and Kalra, Philip A. and Kalra, Paul R.
Identification Number:
10.1016/j.jacc.2024.08.052
Date:
29 October 2024
Divisions:
College of Medical Veterinary and Life Sciences > School of Cancer Sciences
College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care
Publisher:
Elsevier
Additional Information:
The IRONMAN trial was funded by the British Heart Foundation (grant CS/15/1/31175). Pharmacosmos supplied ferric derisomaltose and gave additional financial support.
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URI:
https://pub.demo35.eprints-hosting.org/id/eprint/122
Item Type:
Article
Depositing User:
Unnamed user with email ejo1f20@soton.ac.uk
Date Deposited:
11 Jun 2025 16:35
Revision:
40
Last Modified:
12 Jun 2025 11:26
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