Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

Abstract

There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical value. The aim of this systematic review was to summarize and evaluate endpoints used to assess appetite and dietary intake in cancer cachexia clinical trials. A search for studies published from 1 January 1990 until 2 June 2021 was conducted using MEDLINE, Embase and Cochrane Central Register of Controlled Trials. Eligible studies examined cancer cachexia treatment versus a comparator in adults with assessments of appetite and/or dietary intake as study endpoints, a sample size ≥40 and an intervention lasting ≥14 days. Reporting was in line with PRISMA guidance, and a protocol was published in PROSPERO (2022 CRD42022276710). This review is part of a series of systematic reviews examining cachexia endpoints. Of the 5975 articles identified, 116 were eligible for the wider review series and 80 specifically examined endpoints of appetite (65 studies) and/or dietary intake (21 studies). Six trials assessed both appetite and dietary intake. Appetite was the primary outcome in 15 trials and dietary intake in 7 trials. Median sample size was 101 patients (range 40–628). Forty-nine studies included multiple primary tumour sites, while 31 studies involved single primary tumour sites (15 gastrointestinal, 7 lung, 7 head and neck and 2 female reproductive organs). The most frequently reported appetite endpoints were visual analogue scale (VAS) and numerical rating scale (NRS) (40%). The appetite item from the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) C30/C15 PAL (38%) and the appetite question from North Central Cancer Treatment Group anorexia questionnaire (17%) were also frequently applied. Of the studies that assessed dietary intake, 13 (62%) used food records (prospective registrations) and 10 (48%) used retrospective methods (24-h recall or dietary history). For VAS/NRS, a mean change of 1.3 corresponded to Hedge's g of 0.5 and can be considered a moderate change. For food records, a mean change of 231 kcal/day or 11 g of protein/day corresponded to a moderate change. Choice of endpoint in cachexia trials will depend on factors pertinent to the trial to be conducted. Nevertheless, from trials assessed and available literature, NRS or EORTC QLQ C30/C15 PAL seems suitable for appetite assessments. Appetite and dietary intake endpoints are rarely used as primary outcomes in cancer cachexia. Dietary intake assessments were used mainly to monitor compliance and are not validated in cachexia populations. Given the importance to cachexia studies, dietary intake endpoints must be validated before they are used as endpoints in clinical trials.

People
Vagnildhaug, Ola Magne
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Balstad, Trude R.
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Ottestad, Inger
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Bye, Asta
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Greil, Christine
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Arends, Jann
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Baracos, Vickie
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Brown, Leo R.
Author

Brown, Leo R. and Thomson, Georgina G. and Gardner, Ellen and Chien, Siobhan and McGovern, Josh and Dolan, Ross D. and McSorley, Stephen T. and Forshaw, Matthew J. and McMillan, Donald C. and Wigmore, Stephen J. and Crumley, AndrewB. and Skipworth, Richard J.E. (2024) Cachexia index for prognostication in surgical patients with locally advanced oesophageal or gastric cancer: multicentre cohort study. British Journal of Surgery, 111 (4): znae098. ISSN 0007-1323

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Dajani, Olav F.
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Dolan, Ross D.
Author

Thompson, Joshua J. and MacLeod, Nicholas and Will, Sarah and O'Rourke, Fraser and McGovern, Josh and Roxburgh, Campbell and Edwards, Joanne and Dolan, Ross D. and McMillan, Donald C. (2025) The prognostic value of a laboratory cachexia score (LCAS) defined by LDH, CRP and albumin in patients with advanced lung cancer. BMC Cancer, 25: 543. ISSN 1471-2407

Dolan, Ross D. and Pennel, Kathryn and Thompson, Joshua and McKenzie, Molly and Alexander, Peter and Richards, Colin and Black, Douglas and Abbass, Tanvir and Maka, Noori and McGovern, Josh and Roseweir, Antonia and McSorley, Stephen T. and Horgan, Paul G. and Roxburgh, Campbell and McMillan, Donald C. and Edwards, Joanne (2025) The relationship between tumour necrosis, systemic inflammation, body composition and survival in patients with colon cancer. BJC Reports, 3 (1): 7. ISSN 2731-9377

Golder, Allan M. and Ferguson, Michael and McMillan, Paul and Mansouri, David and Horgan, Paul G. and Roxburgh, Campbell S. and Dolan, Ross D. and McGovern, Josh and McMillan, Donald (2024) CT-derived body composition and differential association with age, TNM stage and systemic inflammation in patients with colon cancer. Scientific Reports, 14: 15673. ISSN 2045-2322

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Fallon, Marie
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Fraser, Eilidh
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Grzyb, Aleksandra
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Hjermstad, Marianne J.
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Jakobsen, Gunnhild
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Kaasa, Stein
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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McDonald, James
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Philips, Iain
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Sayers, Judith
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Simpson, Melanie R.
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Sousa, Mariana S.
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Skipworth, Richard J.E.
Author

Brown, Leo R. and Thomson, Georgina G. and Gardner, Ellen and Chien, Siobhan and McGovern, Josh and Dolan, Ross D. and McSorley, Stephen T. and Forshaw, Matthew J. and McMillan, Donald C. and Wigmore, Stephen J. and Crumley, AndrewB. and Skipworth, Richard J.E. (2024) Cachexia index for prognostication in surgical patients with locally advanced oesophageal or gastric cancer: multicentre cohort study. British Journal of Surgery, 111 (4): znae098. ISSN 0007-1323

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Laird, Barry J.A.
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Solheim, Tora S.
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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Cancer Cachexia Endpoints Working Group
Author

Vagnildhaug, Ola Magne and Balstad, Trude R. and Ottestad, Inger and Bye, Asta and Greil, Christine and Arends, Jann and Baracos, Vickie and Brown, Leo R. and Dajani, Olav F. and Dolan, Ross D. and Fallon, Marie and Fraser, Eilidh and Grzyb, Aleksandra and Hjermstad, Marianne J. and Jakobsen, Gunnhild and Kaasa, Stein and McDonald, James and Philips, Iain and Sayers, Judith and Simpson, Melanie R. and Sousa, Mariana S. and Skipworth, Richard J.E. and Laird, Barry J.A. and Solheim, Tora S. and Cancer Cachexia Endpoints Working Group (2024) Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle, 15 (2). pp. 513-535. ISSN 2190-5991

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