This introduction to the special issue ‘Gender and Work in Twentieth-Century Italy’ draws on key strands of historical scholarship on gender and work, including women workers’ experiences, labour market discrimination, domestic work, the impact of gender norms, and ideas of masculinity and femininity on work identities. It traces the development of feminist influence within this scholarship, from making women workers’ experiences visible to challenging essentialist notions of gender identities. Drawing on post-structuralist and intersectional perspectives, particularly influenced by Joan Wallach Scott and Judith Butler, the scholarship on which this special issue is based understands gender as a system of power signified through language and social constructions, and builds on the critique of the dichotomies and essentialisations of traditional labour history, proposing a systemic and structural approach to understanding gendered experiences of work. By exploring the intersections of gender, work and power, this collection offers insights into wider European developments and challenges established historical concepts and narratives. It highlights the importance of understanding gender dynamics in shaping labour relations and social structures, ultimately contributing to a more nuanced understanding of labour and power dynamics in twentieth-century Italy and beyond.