Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

Abstract

Background:
Treatment options for pre-treated patients with metastatic triple-negative breast cancer (mTNBC) remain limited. This is the first study to assess the real-world safety and efficacy of sacituzumab govitecan (SG) in the UK.

Methods:
Data was retrospectively collected from 16 tertiary UK cancer centres. Pts had a diagnosis of mTNBC, received at least two prior lines of treatment (with at least one being in the metastatic setting) and received at least one dose of SG.

Results:
132 pts were included. Median age was 56 years (28–91). All patients were ECOG performance status (PS) 0-3 (PS0; 39, PS1; 76, PS2; 16, PS3;1). 75% (99/132) of pts had visceral metastases including 18% (24/132) of pts with CNS disease. Median PFS (mPFS) was 5.2 months (95% CI 4.5–6.6) with a median OS (mOS) of 8.7 months (95% CI 6.8-NA). The most common adverse events (AEs) were fatigue (all grade; 82%, G3/4; 14%), neutropenia (all grade; 55%, G3/4; 29%), diarrhoea (all grade; 58%, G3/4, 15%), and nausea (all grade; 38%, G3/4; 3%). SG dose reduction was required in 54% of pts.

Conclusion:
This study supports significant anti-tumour activity in heavily pre-treated pts with mTNBC. Toxicity data aligns with clinical trial experience.

People
Hanna, Daire
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Merrick, Sophie
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Ghose, Aruni
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Devlin, Michael John
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Yang, Dorothy D.
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Phillips, Edward
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Okines, Alicia
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Chopra, Neha
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Papadimatraki, Elisavet
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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ROSS, KIRSTY
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Macpherson, Iain R.
Author

Maldonado, Horacio and Dreger, Marcel and Bedgood, Lara D. and Kyriakou, Theano and Wolanska, Katarzyna I. and Rigby, Megan E. and Marotta, Valeria E. and Webster, Justine M. and Wang, Jun and Rusilowicz-Jones, Emma V. and Marshall, John F. and Coulson, Judy M. and MacPherson, Iain R. and Hurlstone, Adam and Morgan, Mark R. (2024) A trafficking regulatory subnetwork governs α V β 6 integrin-HER2 cross-talk to control breast cancer invasion and drug resistance. Science Advances, 10 (49): eadk9944. ISSN 2375-2548

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

Agnew, Sommer and Crawford, Megan and MacPherson, Iain and Shiramizu, Victor and Fleming, Leanne (2024) The impact of symptom clusters on endocrine therapy adherence in patients with breast cancer. Breast, 75: 103731. ISSN 0960-9776

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Boh, Zhuang Y.
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Michie, Caroline O.
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Swampillai, Angela
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Gupta, Sunnia
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Robinson, Tim
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Germain, Lewis
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Twelves, Chris
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Atkinson, Charlotte
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Konstantis, Apostolos
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Riddle, Pippa
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Cresti, Nicola
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Naik, Jay D.
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Borley, Annabel
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

Henriksen, Peter A. and Hall, Peter and MacPherson, Iain R. and Joshi, Shruti S. and Singh, Trisha and Maclean, Morag and Lewis, Steff and Rodriguez, Aryelly and Fletcher, Alexander and Everett, Russell J. and Stavert, Harriet and Broom, Angus and Eddie, Lois and Primrose, Lorraine and McVicars, Heather and McKay, Pam and Borley, Annabel and Rowntree, Clare and Lord, Simon and Collins, Graham and Radford, John and Guppy, Amy and Williams, Michelle C. and Japp, Alan and Payne, John R. and Newby, David E. and Mills, Nick L. and Oikonomidou, Olga and Lang, Ninian N. (2023) Multicenter, prospective, randomized controlled trial of high-sensitivity cardiac troponin I–guided combination angiotensin receptor blockade and beta-blocker therapy to prevent anthracycline cardiotoxicity: The Cardiac CARE trial. Circulation, 148 (21). pp. 1680-1690. ISSN 0009-7322

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Guppy, Amy
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

Henriksen, Peter A. and Hall, Peter and MacPherson, Iain R. and Joshi, Shruti S. and Singh, Trisha and Maclean, Morag and Lewis, Steff and Rodriguez, Aryelly and Fletcher, Alexander and Everett, Russell J. and Stavert, Harriet and Broom, Angus and Eddie, Lois and Primrose, Lorraine and McVicars, Heather and McKay, Pam and Borley, Annabel and Rowntree, Clare and Lord, Simon and Collins, Graham and Radford, John and Guppy, Amy and Williams, Michelle C. and Japp, Alan and Payne, John R. and Newby, David E. and Mills, Nick L. and Oikonomidou, Olga and Lang, Ninian N. (2023) Multicenter, prospective, randomized controlled trial of high-sensitivity cardiac troponin I–guided combination angiotensin receptor blockade and beta-blocker therapy to prevent anthracycline cardiotoxicity: The Cardiac CARE trial. Circulation, 148 (21). pp. 1680-1690. ISSN 0009-7322

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Schmid, Peter
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Phillips, Melissa
Author

Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa (2024) Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom. British Journal of Cancer, 130 (12). pp. 1916-1920. ISSN 0007-0920

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Title:
Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom
Creators:
Hanna, Daire and Merrick, Sophie and Ghose, Aruni and Devlin, Michael John and Yang, Dorothy D. and Phillips, Edward and Okines, Alicia and Chopra, Neha and Papadimatraki, Elisavet and ROSS, KIRSTY and MacPherson, Iain and Boh, Zhuang Y. and Michie, Caroline O. and Swampillai, Angela and Gupta, Sunnia and Robinson, Tim and Germain, Lewis and Twelves, Chris and Atkinson, Charlotte and Konstantis, Apostolos and Riddle, Pippa and Cresti, Nicola and Naik, Jay D. and Borley, Annabel and Guppy, Amy and Schmid, Peter and Phillips, Melissa
Identification Number:
10.1038/s41416-024-02685-9
Date:
29 June 2024
Divisions:
College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Publisher:
Nature Publishing Group
Library
URI:
https://pub.demo35.eprints-hosting.org/id/eprint/221
Item Type:
Article
Depositing User:
Unnamed user with email ejo1f20@soton.ac.uk
Date Deposited:
11 Jun 2025 16:36
Revision:
14
Last Modified:
12 Jun 2025 10:45
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